FGviewer:
a tool for visualizing
functional features of human fusion gene
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I. Signal transduction without control
: BCR-ABL1 (chr22:23182239-chr9:130854061)
go to
FGviewer
or
FusionGDB
II. Target gene activation
: EWSR1-FLI1 (chr22:29287134-chr11:128805366)
go to
FGviewer
or
FusionGDB
III. Lost protein-protein interaction
: KMT2A-MLLT10 (chr11:118482094-chr10:21713769)
go to
FGviewer
or
FusionGDB
IV. Avoid of miRNA regulation
: FGFR3-TACC3(chr4:1806934-chr4:1735272)
go to
FGviewer
or
FusionGDB
V. Up-regulate downstream effectors
: NUP214-ABL1 (chr9:131151894-chr9:130872128)
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FGviewer
or
FusionGDB
VI. Gain or loss of cellular regulatory subunit
: SS18-SSX (chr18:26032398-chrX:48263781)
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FGviewer
or
FusionGDB
* Novel FG from one dbVar study (nstd33)
: CELF6-TMEM266 (chr15:72287314-chr15:76134313)
go to
FGviewer
or
FusionGDB